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Huynh Dinh Chien

Huynh Dinh Chien, MD., PhD.

College of Health Sciences

Professor

Lab Director

Year 1 Chair, Medical Doctor Program

Biography

Dr. Huynh Dinh Chien is a dedicated medical teacher who emphasizes medical care activities for poor communities, especially ethnic minorities in Central Vietnam. After being granted his PhD degree in Immunology in Hungary in 1989, he engaged in research on immunology and poverty reduction, particularly in ethnic minority areas. Building clinical trial areas for new antimalarial drugs is the focus of his ongoing research. Dr. Chien has compiled and published 14 books (3 in English), published more than 40 scientific articles in international journals, participated as a presenter in 13 international conferences, and many domestic workshops and seminars. He was awarded the title Associate Professor in 2002 and Full Professor in 2009. Dr. Chien has been invited to act as a consultant for many international projects at non-governmental organizations as well as at the Ministry of Health. He joined Vinmec Health System in 2017 and was introduced to work at VinUni since 2019.

  1. Immunological aspects of healthy people and the patients of some relevant illnesses such as infectious diseases, cancers.
  2. Treatment for drug-resistant malaria.

  • Immunology and Allergology
  • Clinical Laboratory Methods

  1. K. Meretey, K. Arvai, T. Lakatos, E. Walcz, A. Falus, H. D. Chien. Immunoglobulin Production of Synovial Fragments Cultured in vitro. Clinical and Experimental Rheumatology. Number 5/S-2. P 275. 1987
  2. H.D. Chien, E. Walcz, T. Lakatos, K. Arvai, M. Brozik, K. Meretey. Immunoglobulins in Synovial Fragment Culture. Magyar Reumatologia. Number 24. pp 57-63. 1988
  3. T. Neumark, H.D. Chien. Gap Junctions between Human T-Colony Cells. Acta Morphologica Hungarica. Number 37. pp 147-153. 1989
  4. K. Meretey, H.D. Chien, A. Falus, E. Walcz. Effect of Histamine on the T-Cell Colony Formation of PHA-Stimulated Cells. Agents and Actions. Number 1/2. pp 215-217. 1989
  5. K. Meretey, D.C. Huynh, A. Falus, M. Brozik. Humoral Factors and Surface Markers in the T-Cell Colony Formation in RA Patients. Clinical Rheumatology. Number 9. p 119. 1990
  6. G. Hittner, H.D. Chien, K. Meretey. Depressed T-Colony Formation in Rheumatoid Arthritis and the Role of Endogenously Produced PGE2 and IL-1. Magyar Reumatologia. Number 32. pp 229-235. 1991
  7. (Vietnamese) N.D. Hai, H.T. Tan, P.G.A. Bao, H.D. Chien. Preliminary Study on Prediction of Shock Syndrome in Patients of Dengue Fever Using Some Immunological Indices. Nghien Cuu va Thong Tin Y Hoc, Hue Medical School. Number 2. pp 65-69. 1992
  8. D.C. Huynh, M. Brozik, M. Szongoth, U. Bohm, K. Meretey. Immunoblot Analysis of Autoantibody Isotypes in SLE. Clinical Rheumatology. Volume 13. Number 1. p 154. 1994
  9. K. Meretey, D.C. Huynh, M. Brozik, I. Szuts, U. Bohm, G. Fernez. Antibody Isotypes in Primary Sjogren Syndrome. Clinical Rheumatology. Volume 13. Number 1. pp 159-160. 1994
  10. (English and Chinese) H.D. Chien. HIV Infection and Sexual Education in Vietnam: A Brief Report. Proceeding of the First Asian Congress on Sexual Education. Beijing, 23-25 August 2001
  11. Kesely, K., Low, P. S., Chien, H. D., Pantaleo, A . , Turrini, F. Investigating Syk Tyrosine Kinase and its Critical Involvement in Parasite Egress from Malaria Infected Erythrocytes. Poster at the World Congress on Malaria in New York, USA, 2014
  12. Antonella Pantaleo, Maria Carmina Pau, Huynh Dinh Chien, Francesco Turrini. Artemisinin resistance, some facts and opinions. J Infect Dev Ctries; 9(6):597-599. DOI:10.3855/jidc.7015. 2015
  13. Antonella Pantaleo, Kristina R. Kesely, Maria Carmina Pau, Ioannis Tsamesidis, Evelin Schwarzer, Oleksii A. Skorokhod, Huynh D. Chien, Marta Ponzi, Lucia Bertuccini, Philip S. Low and Francesco M. Turrini. Syk Inhibitors interfere with erythrocyte membrane modification during P. falciparum growth and suppress parasite egress. Blood; (2017) pre-published online June 20, 2017; DOI 10.1182/blood-2016-11-748053
  14. Karen E. Yannell, Kristina R. Kesely, Huynh Dinh Chien, Candice B. Kissinger, R. Graham Cooks. Comparison of paper spray mass spectrometry analysis of dried blood spots from devices used for in-field collection of clinical samples. Anal Bioanal Chem (2017) 409:121–131 pre-published online: DOI10.1007/s00216-016-9954-5.
  15. Maria Carmina Pau, Antonella Pantaleo, Ioannis Tsamesidis, Ha Hoang, Anh Tuan Tran, Thi Lien Hanh Nguyen, Thi Hang Giang Phan, Phuong Anh Ton Nu, Thi Minh Chau Ngo, Giuseppe Marchetti, Evelin Schwarzer, Pier Luigi Fiori, Philip S. LowID, Chien Dinh Huynh, Francesco Michelangelo Turrini. Clinical impact of the two ART resistance markers, K13 gene mutations and DPC3 in Vietnam. PLoS ONE (2019) 14(4): e0214667. https://doi.org/10.1371/journal.pone.0214667.
  16. Francesco M. Turrini, Philip S. Low, Huynh Dinh Chien. A Novel Strategy for P. falciparum Malaria based on Syk Kinase Inhibitors to Design Triple Artemisinin- based Combination Therapies (TACTs) to Counteract Delayed Parasite Clearance (Drug Resistance) Following Standard ACT Treatment. Interventional Medicine and Clinical Imaging (2021), (4) 1: 2-4, published online DOI: 10.31038/IMCI.2021411
  17. Chien HD, Pantaleo A, Kesely KR, Noomuna P, Putt KS, Tuan TA, Low PS, Turrini FM. Imatinib augments standard malaria combination therapy without added toxicity. J Exp Med. (2021). 218(10):e20210724. doi: 10.1084/jem.20210724. Epub 2021 Aug 26. PMID: 34436509; PMCID: PMC8404470.
  18. Thuy MH, Duy H, Chien DH, Linh L. Integrated Educational Technology in Teaching Anatomy Using the ASIC Framework: A Case Study from VinUniversity. Adv in Med Edu and Prac. (2023). 14: 669-681. DOI:10.2147/AMEP.S405340

  • Master’s, Education Management, RMIT, Australia, 2004
  • PhD, Immunology, National Institute of Rheumatology and Physiotherapy, Hungary, 1989
  • Specialization Doctor Level I, Hygiene and Epidemiology, Hanoi Medical School, Vietnam, 1984
  • MD, Medical School, Hue University, Vietnam, 1980

PATENT N. 102016000077844 awarded by The Ministry of Economic Development, Italian Government on 25/01/2019: – Inventors: (1) Turrini Francesco Michelangelo, (2) Huynh Dinh Chien, (3) Pantaleo Antonella, (4) Tsamesidis Ioannis, (5) Low Philip Stewart – Patent Title: “The use of the synergic action of of human syk inhibitors for the preparation of new therapeutic combinations based on artemisinin (ACTs) for the radical treatment of malaria”.

Google Scholar ID: click here

ORCID: click here

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