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Hoang Mai Tran, MSc

College of Health Sciences

Medical Scientist

Biography

Ms. Tran Hoang Mai holds a Bachelor’s degree in Biology (Molecular Genetics) from Vietnam National University, Hanoi, and a Master’s degree in Biomedical Science from the School of Medicine, Ajou University, South Korea. She began her research career in 2017 at the Vinmec Research Institute of Stem Cell and Gene Technology, and subsequently worked at the Vietnam–German Medical Research Center (108 Military Central Hospital) and the VinBigData Research Institute, Vingroup (2018–2024), where she contributed to the 1000 Vietnamese Genome Project. From 2022 to 2024, she also served as Laboratory Manager at GeneStory JSC.
Since 2024, Ms. Tran has been a researcher at the Vinmec–VinUniversity Institute of Immunology. Her research focuses on population genetics, disease risk prediction, genetic mechanisms underlying drug allergies, and the genetic diagnosis and prognosis of allergic and autoimmune diseases. She has authored and co-authored multiple international journal articles and book chapters and is the co-inventor of patents that have been successfully applied in practice. In addition, she has joined the training courseư at NIH, USA, as well as had been a research fellow of the SPRING Program funded by the Japan Science and Technology Agency (JST).

  1. Dinh NV, Trang TTH, Mai TH, Nam NL, Nam NN, Tien PM, Quang VT, Anh NQ, Mai VT, Yen PTH, Thang NV, Lan PQ, Nguyet NTM, Oanh HT, Thuy CTT, Anh DT, Nguyet NN, Hang VT, Sheryl NV, Timothy CJ, Nam VS, Hieu CC. “Polygenic Risk Score of Common Genetic Variants for NSAIDS Hypersensitivity Prediction in Vietnamese”. The Journal of Allergy and Clinical Immunology v. 153, 2, sup, Ab157, Feb 2024. https://doi.org/10.1016/j.jaci.2023.11.515.
  2. Hoang, C.Q., Duong, G.H., Tran, M.H. et al. “Molecular mechanisms underlying phenotypic degeneration in Cordyceps militaris: insights from transcriptome reanalysis and osmotic stress studies”. Sci Rep 14, 2231 (2024). https://doi.org/10.1038/s41598-024-51946-3
  3. Thanh NN, Mai HT, Quoc HV, Thi LL, Mai NAV, Thi TTC, Mai TV, Anh QN, Yen PTH, Huong LTM, Timothy C., Sheryl VN, Thi QND, Van KN, Nhu NN, Thi HV, Nam SV, Hieu CC, Dinh VN. (2023), P19: “MACHINE LEARNING FOR PREDICTION MODEL OF SEVERE CUTANEOUS ADVERSE DRUG REACTIONS IN VIETNAMESE”. Intern Med J, 53: 10-10. https://doi.org/10.1111/imj.18_16230
  4. Duy Pham, Buu Truong, Khai Tran, Guiyan Ni, Dat Nguyen, Trang T H Tran, Mai H Tran, Duong Nguyen Thuy, Nam S Vo, Quan Nguyen. “Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam”. Briefings in Bioinformatics, Volume 23, Issue 6, November 2022, bbac459, https://doi.org/10.1093/bib/bbac459
  5. Trang T. H Tran, Mai Tran Hoang et al. “Polygenic risk scores adaptation for Height in Vietnamese population”. The 14th IEEE International Conference on Knowledge and Systems Engineering (KSE) 2022. – pp. 1-7, https://doi.org/10.1109/KSE56063.2022.9953620
  6. Nguyen KH*, Nguyen QA*, Tran MH*, Can TT, Vu MT & Vo NS et al. “Autosomal recessive hyper-IgE syndrome due to DOCK8 deficiency: An adjunctive role for omalizumab”. J Cutan Immunol Allergy. 2022; 5: 222– 226. https://doi.org/10.1002/cia2.12273 (Co-first author)
  7. Nguyen, D.T., Tran, T.T.H., Tran, M.H. et al. A comprehensive evaluation of polygenic score and genotype imputation performances of human SNP arrays in diverse populations. Sci Rep 12, 17556 (2022). https://doi.org/10.1038/s41598-022-22215-y
  8. Hoang, T.H., Vu, G.M., Tran, M.H. et al “Investigation of target sequencing of SARS-CoV-2 and immunogenic GWAS profiling in host cells of COVID-19 in Vietnam”. BMC Infectious Diseases (2022) 22:558. https://doi.org/10.1186/s12879-022-07415-1
  9. Hoang, C. Q., Duong, H., Nguyen, N. T., Nguyen, S. A., Nguyen, C., Nguyen, B. D., Phung, L. T., Nguyen, D. T., Pham, C. T., Le Doan, T., Tran, M. H.”Clinical evaluation of RB1 genetic testing reveals novel mutations in Vietnamese patients with retinoblastoma”. Molecular and Clinical Oncology 15.3 (2021): 182. https://doi.org/10.3892/mco.2021.2344
  10. Tran MH, Seo E, Min S, Nguyen QT, Choi J, Lee UJ, Hong SS, Kang H, Mansukhani A, Jou I, Lee SY. “NEDD4-induced degradative ubiquitination of phosphatidylinositol 4-phosphate 5-kinase a and its implication in breast cancer cell proliferation”. Journal of Cellular and Molecular Medicine. 2018 Sep;22(9):4117-4129. https://doi.org/10.1111/jcmm.13689
  11. Le OT, Cho OY, Tran MH, Kim JA, Chang S, Jou I, Lee SY. “Phosphorylation of phosphatidylinositol 4- phosphate 5- kinase y by Akt regulates its interaction with talin and focal adhesion dynamics”. BBA – Molecular Cell Research. 2015 Oct;1853(10 Pt A):2432-43. https://doi.org/10.1016/j.bbamcr.2015.07.001

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