Abstract To examine gene expression in different clinical phenotypes of allopurinol-induced severe cutaneous adverse reactions (SCARs). Materials & methods: Gene expression profiling was performed using microarray on 11 RNA samples (four controls, three hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms, four Stevens–Johnson syndrome/toxic epidermal necrolysis) followed by quantitative real-time PCR in a total of 11 SCARs patients […]

Abstract Aim: Anoxic brain injury (ABI) due to non-fatal drowning may cause persistent vegetative state (VS) that is currently incurable. The aim of this paper is to present the safety and feasibility of autologous bone marrow-derived mononuclear cell (BMMNC) transplantation in five drowning children surviving in persistent VS. Methods: We used BMMNC as a novel […]

Abstract Harm events such as pneumothoraces and pneumonia continue to be associated with feeding tube insertion. Most bedside verification methods are not accurate to discriminate pulmonary from gastrointestinal system. Evidence-based clinical practice guidelines do not support auscultation of feeding tubes in adults, yet auscultation is the most common method used. Authors: Upvall, M.J. and other […]

Abstract Monte Carlo integration is an efficient method to solve a high-dimensional integral in light transport simulation, but it typically produces noisy images due to its stochastic nature. Many existing methods, such as image denoising and gradient-domain reconstruction, aim to mitigate this noise by introducing some form of correlation among pixels. While those existing methods […]

Abstract Hyperphosphatemia is the primary risk factor for vascular calcification, which is closely associated with cardiovascular morbidity and mortality. Recent evidence showed that oxidative stress by high inorganic phosphate (Pi) mediates calcific changes in vascular smooth muscle cells (VSMCs). However, intracellular signaling responsible for Pi-induced oxidative stress remains unclear. Here, we investigated molecular mechanisms of […]

Abstract The cumulative of genes carrying mutations is vital for the establishment and development of cancer. However, this driver gene exploring research line has selected and used types of tools and models of analysis unsystematically and discretely. Also, the previous studies may have neglected low-frequency drivers and seldom predicted subgroup specificities of identified driver genes. […]

Abstract Buy-Online-Pick-up-in-Store (BOPS) service is a popular omnichannel retail initiative, intended to enhance the convenience of online customers. Focusing on the pick-up (PU) stage of BOPS service, we develop a comprehensive scale (BOPS-PU-QUAL) for its quality perceived by customers. A multi-step scale development procedure involving one qualitative and two quantitative studies resulted in a scale […]

Abstract We present theoretically the formation of exciton–photon polaritons and exciton-surface plasmon polaritons in a perovskite-based subwavelength lattice on the metallic plane. It is shown that the later polaritons will be achieved as the perovskite layer is ultra-thin (<50 nm), while the co-existence of both polaritons will dominate, as the thickness of the perovskite metasurface […]

Abstract We investigate the local and global dynamics of two 1-Dimensional (1D) Hamiltonian lattices whose inter-particle forces are derived from nonanalytic potentials. In particular, we study the dynamics of a model governed by a “graphene-type” force law and one inspired by Hollomon’s law describing “work-hardening” effects in certain elastic materials. Our main aim is to […]

Abstract Background and Aims The present study analyzes the relation between diet and all-cause mortality in a cohort of Italian men residing in different regions of Italy. Methods and Results The cohort was established using the members of the Associazione Nazionale Alpini, a voluntary organization that enlists individuals who have served in the Alpine troup; […]