The Silent Development of Vascular Calcification in Chronic Kidney Disease Patients
Speaker: Nguyen Thi Nhung, Lecturer, College of Health Sciences
Abstract
Chronic kidney disease (CKD) is a significant contributor to morbidity and mortality from non-communicable diseases, but it often remains asymptomatic until the stage of the disease progresses. In 2017, the number of individuals with all-stage CKD reached almost 700 million in which diabetes and hypertension are the main causes of CKD. In fact, Vietnam is among the top 10 countries in the Asia-Pacific region with the fastest rate of type 2 diabetes (T2DM) and CKD development. Patients not only exhibit renal deterioration but also suffer many unfavorable complications associated with CKD including vascular calcification, muscle wasting, sarcopenia, and cachexia. These complications without diagnosis and intervention at the early stage of CKD largely affect the patients’ life. However, there is little understanding of this connection in CKD patients. Therefore, understanding the underlying mechanisms of vascular calcification in CKD patients could benefit patients to gain a better life.
