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Nguyen Van Dinh

Nguyen Van Dinh, MD, PhD

College of Health Sciences

Chair of Clinical Allergy and Immunology

Research Institute of Immunology

Director

Biography

Associate Professor Nguyen Van Dinh, MD, PhD has over 15 years of experience in Allergy, Clinical Immunology, and Medical Education. Professor Dinh currently serves as Director of the Vinmec – VinUni Institute of Immunology and Director of the Allergy and Clinical Immunology Center at Vinmec Times City International Hospital. He is an active member of several leading international professional societies, including AAAAI, EAACI, WAO và APAACI. He also contributes to international guideline development and expert committees, including the WAO Cutaneous Allergy Working Group and the APAACI Drug Hypersensitivity Committee. Professor Dinh has successfully supervised six master’s students, eight VinUniversity resident physicians, and one PhD candidate. He currently supervises five doctoral candidates at universities in Vietnam and internationally. In addition, he holds honorary and adjunct clinical associate professorship appointments at the Penn State College of Medicine and the University of Sydney.

His research focuses on pharmacogenomics in drug hypersensitivity, with notable contributions to understanding the association between HLA variants and severe cutaneous adverse reactions (SCARs).

He has authored one monograph, five book chapters, 36 articles in national journals, and 39 ISI/Scopus-indexed publications. His work has received more than 1,200 citations, with an H-index of 14. Professor Dinh serves as a reviewer for several high-impact journals, including Allergy and The Pharmacogenomics Journal. He has led numerous research projects in pharmacogenomics, allergen immunotherapy, hereditary angioedema, and atopic dermatitis.

  • Description of 3 cases in Vietnam of aspirin desensitization in patients with coronary artery disease and coexisting aspirin hypersensitivity. World Allergy Organization Journal. 2012;5(11):170–173. https://doi.org/10.1016/S1939-4551(19)30397-7
  • HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in Vietnamese. Asia Pacific Allergy. 2015;5(2):68–77. (Synapse record).
  • Validation of a rapid test for HLA-B*58:01/57:01 allele screening to detect individuals at risk for drug-induced hypersensitivity. Pharmacogenomics. 2016;17(5):473–480. https://doi.org/10.2217/pgs.15.185
  • Validation of a novel real-time PCR assay for detection of HLA-B*15:02 allele for prevention of carbamazepine-induced Stevens–Johnson syndrome/Toxic Epidermal Necrolysis in individuals of Asian ancestry. Human Immunology. 2016;77(12):1140–1146. https://doi.org/10.1016/S0198-8859(16)30419-0
  • Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B*58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions. Allergy, Asthma & Immunology Research. 2017;9(1):79–84. (Synapse record)
  • A novel multiplex polymerase chain reaction assay for detection of both HLA-A31:01/HLA-B15:02 alleles, which confer susceptibility to carbamazepine-induced severe cutaneous adverse reactions. HLA: Immune Response Genetics. 2017;90(6):335–342. https://doi.org/10.1111/tan.13143
  • Developing pharmacogenetic screening methods for an emergent country: Vietnam. World Allergy Organization Journal. 2019;12(5):1–10. https://doi.org/10.1016/S1939-4551(19)30666-0
  • Human leukocyte antigen-associated severe cutaneous adverse drug reactions: from bedside to bench and beyond. Asia Pacific Allergy. 2019;9(3):e20, 1–24. (Synapse record)
  • Drug-induced severe cutaneous adverse reactions: Determine the cause and prevention. Annals of Allergy, Asthma & Immunology. 2019;123(5):483–487. https://doi.org/10.1016/j.anai.2019.10.006
  • Successful management of severe diabetic ketoacidosis in a patient with type 2 diabetes with insulin allergy: a case report. BMC Endocrine Disorders. 2019;19:121. https://doi.org/10.1186/s12902-019-0451-7
  • Gene expression profiling in allopurinol-induced severe cutaneous adverse reactions in Vietnamese. Pharmacogenomics. 2020;21(14):985–994. https://doi.org/10.2217/pgs-2020-0014
  • Genetic susceptibilities and prediction modeling of carbamazepine and allopurinol-induced severe cutaneous adverse reactions in Vietnamese. Pharmacogenomics. 2020;21(14):1–12. https://doi.org/10.2217/pgs-2019-0146
  • Review on Databases and Bioinformatic Approaches on Pharmacogenomics of Adverse Drug Reactions. Pharmacogenomics and Personalized Medicine. 2021;14:61–75. (PMC full text) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812041/
  • A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People. The Application of Clinical Genetics. 2021;14:27–35. https://doi.org/10.2147/TACG.S278652
  • A novel nested allele-specific PCR protocol for the detection of the HLA-A*33:03, a SCAR-associated allele, in Vietnamese people. Asian Pacific Journal of Allergy and Immunology. 2021;[AP-201120-1000]. (PubMed record) PMID: 33865300
  • Utility of skin testing in assessment of post-AZD1222 vaccine (AstraZeneca) allergic reactions: case series in Vietnam. Asia Pacific Allergy. 2021;11(4):e40:1–6. (PMC full text) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563096/
  • Allopurinol-induced severe cutaneous adverse reactions in Vietnamese: the role of HLA alleles and other risk factors. Pharmacogenomics. 2022;23(5):303–313. https://doi.org/10.2217/pgs-2021-0156
  • The utility of surrogate markers in predicting HLA alleles associated with adverse drug reactions in Vietnamese. Asian Pacific Journal of Allergy and Immunology. 2022;40(2):134–141. doi:10.12932/AP-170219-0493. PMID: 31421661
  • The international WAO/EAACI guideline for the management of hereditary angioedema — The 2021 revision

He earned his Doctor of Medicine degree from the Hanoi Medical University in 2007 and completed his residency training in Allergy and Clinical Immunology with distinction in 2011. Supported by the prestigious Australia Awards Scholarship, he obtained his PhD in Medicine from the University of Sydney in 2018. In 2023, he completed the Health Professions Education Program at the University of Pennsylvania.

His achievements have been recognized through several prestigious awards, including:
• APAACI Best Paper Award (2013)
• HocMai Foundation President’s Award at the University of Sydney (2016)
• Asia Pacific Allergy Best Paper of the Year Award (2018)
• APSR Allergy and Clinical Immunology Award (2019)
• VinUniversity Internal Medicine Residency Program Outstanding Teaching Award (2021)
• VinUniversity Outstanding Faculty Award (2026).

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